Cell types that constitute the bone marrow stroma include: Cellular components. For instance, they generate colony stimulating factors, which have a significant effect on hematopoiesis. Though not as active as parenchymal red marrow, stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. The stroma of the bone marrow is all tissue not directly involved in the marrow's primary function of hematopoiesis.
In cases of severe blood loss, the body can convert yellow marrow back to red marrow to increase blood cell production. Yellow marrow is found in the medullary cavity, the hollow interior of the middle portion of short bones. Red marrow is found mainly in the flat bones, such as the pelvis, sternum, cranium, ribs, vertebrae and scapulae, and in the cancellous (. With age, more and more of it is converted to the yellow type only around half of adult bone marrow is red. Both types of bone marrow contain numerous blood vessels and capillaries.
Red blood cells, platelets, and most white blood cells arise in red marrow.
The hematopoietic component of bone marrow produces approximately 5.Īdditionally, bone marrow stem cells have been successfully transformed into functional neural cells. In humans, red blood cells are produced by cores of bone marrow in the heads of long bones in a process known as hematopoiesis. Bone marrow is the flexible tissue in the interior of bones.
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